Neonatal seizures

Posted by & filed under Part 28: NEUROGENETICS.

Neonatal seizures: Aetiology by means of a standardized work-up. Loman et al. Eur J Paediatr Neurol. 2014 Feb 17. PMID: 24630570

This study explored the incidence of different aetiologies of neonatal seizures in a real cohort of patients. All full-term born neonates from January 2002 till September 2009 with neonatal seizures, admitted to the local neonatal ICU were included (n = 221). Aetiology was investigated by means of a standardized aetiologic work-up.

The most frequent aetiologies of neonatal seizures were:

  • hypoxic-ischemic encephalopathy (HIE) (53.9%),
  • metabolic or electrolyte disorders (10.9%),
  • intracranial hemorrhage (9.0%),
  • ischemic infarction (7.2%),
  • intracranial infections (6.3%),
  • congenital malformations of the central nervous system (3.2%),
  • inborn errors of metabolism (2.3%),
  • epileptic syndromes (0.5%)

Posted by Yannis Trakadis, MD

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