Tachibana et al. demonstrated that the nucleus of an affected woman’s egg could be inserted into healthy donor egg cytoplasm by spindle transfer, allowing the birth of healthy offspring. A child born as a result of this technique will be the genetic child of the patient but carry healthy mitochondrial genes from the donor.
Towards germline gene therapy of inherited mitochondrial diseases. Tachibana et al. Nature. 2013 Jan 31;493(7434):627-31. PMID: 23103867
Posted by Yannis Trakadis, MD