It is now feasible to sequence an individualâ€™s whole genome at a relatively low cost. However, for genome sequencing to be implemented clinically, a number of major challenges need to be overcome. I hereby discuss the challenges associated with integrating genomic technologies into clinical practice and describe a novel approach, namely, â€œIndividualized Mutation-weighed On-line Phenotype Searchâ€ (I-MPOS), and its potential benefits.
In my opinion, this approach could potentially render widespread use of genomic technologies, in the immediate future, practical, ethical and clinically useful, even at the newborn period. What are your thoughts on this?
Patient-controlled encrypted genomic data: an approach to advance clinical genomics.Â Trakadis YJ. BMC Med Genomics. 2012 Jul 20;5(1):31. [Epub ahead of print] PMID: 22818218
Â Yannis Trakadis, MD