A recent study by Bruha et al. suggests that increased oxidative stress may contribute significantly to the clinical manifestation of Wilson disease, an inherited disorder of copper disposition caused by an ATP7B transporter gene mutations.

Decreased serum antioxidant capacity in patients with Wilson disease is associated with neurological symptoms. Bruha et al. J Inherit Metab Dis. 2012 May;35(3):541-8. Epub 2011 Dec 3. PMID: 22139496

posted by Yannis Trakadis MD, MSc