Sudden Bilateral Vision Loss in Methylmalonic Acidemia

Posted by & filed under Part 09: ORGANIC ACIDS.

A recent case report by Traber et al in the Journal of Neuroopthalmology (August 25, 2011 Epub) describes an adult patient with methylmalonic acidemia (MMA) and sudden onset of bilateral vision loss with optic atrophy.  This may not be commonly though of as a frequent adult complication of MMA. However, this sudden onset of vision loss has been described before in adults with methylmalonic acidemia  (MMA) and propionic acidemia (MMA). The largest cohort reported includes 2 adults with MMA and one adult with PA  by Williams et al, in the American Journal of Ophthalmology (2009) 147(5): 929-33.

Hilary Vernon, MD PhD
 

DOI Reference Number : http://dx.doi.org/10.1036/ommbid.121

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