MPS VI gene therapy pre-clinical model

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Mol Genet Metab. 2009 Jun;97(2):102-8. Epub 2009 Feb 27.
Lentiviral-mediated correction of MPS VI cells and gene transfer to joint tissues.
Byers S, Rothe M, Lalic J, Koldej R, Anson DS.

In this publication, the authors use a lentivirus to tranduce human fibroblasts and chondrocytes, as well as the synovial membrane and the fascia in injected rat joints.

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Philippe Campeau

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