I was surprised to see the post stating that older GSD type 1 patients can last 7 hours with a single dose of bedtime cornstarch. Our experience, as well as that of many other families, is that metabolic control is compromised if doses are not delivered Q 4 hours. This has been confirmed by inpatient studies on metabolic units. Even though the patient may be within acceptable limits at the end of the extended time period, studies have shown that there are periods of frank hypoglycemia occuring within the extended time period, and that lactate levels are elevated. Despite the sleep disruption we have elected to keep our child (now aged 15) on a 4 hour overnight schedule.
Comment by GSDmom about excerpt on GSD treatment from OMMBID included in this comment.